Two sample MR report
TOMM7_Monocyte (Mono) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.1643851 | 0.3113125 | 0.6200590 |
| Weighted median | 7 | 0.1181417 | 0.0508411 | 0.0201393 |
| Inverse variance weighted | 7 | 0.1144567 | 0.0418215 | 0.0062042 |
| Simple mode | 7 | 0.1232560 | 0.0706495 | 0.1316678 |
| Weighted mode | 7 | 0.1201124 | 0.0716141 | 0.1445122 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.4913113 | 5 | 0.9924380 |
| Inverse variance weighted | 0.5175058 | 6 | 0.9976189 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0150016 | 0.0926901 | 0.8777631 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 9.02e-05 | 0 | TRUE | 0.3678672 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
